Peri-tonsillar abscess (quinsy) Infections and Infestations Peritonsillar abscess
Conditions
Interventions
Antibiotics (intravenous [IV]) + dexamethasone 8 mg (single dose) vs antibiotics (IV) + placebo
Standard antibiotics treatment would be benzyl-penicillin 1.2 g four times per day (qds) or clarithrom
Sponsors
Raigmore Hospital (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patient with pus aspirated from peri-tonsillar abscess 2. Both males and females, age over 16 3. Minimum body weight of 40 kg
Exclusion criteria
Exclusion criteria: 1. Children less than 16 may not be able to consent themselves to the study so will not be included 2. A body weight of less than 40 kg means the proposed dose of 8 mg dexamethasone is too high 3. Pregnancy 4. Inability to consent 5. Current symptomatic peptic ulcer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Time to resumption of oral intake of fluids and solids 2. Time to resolution of fever 3. Time to resolution of pain | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in inter-incisor distance (i.e. mouth opening as surrogate marker for improvement), measured every 4 hours. | — |
Countries
United Kingdom
Outcome results
None listed