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Evaluation of two dental materials in regenerative treatment of non-vital teeth with incomplete root development

Revascularization of non-vital immature permanent teeth with two bioceramic cements: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN69846868
Enrollment
20
Registered
2024-01-16
Start date
2020-07-01
Completion date
Unknown
Last updated
2024-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Treatment of necrotic immature teeth with apical periodontitis Oral Health

Interventions

Twenty non-vital immature permanent anterior teeth with apical periodontitis were included in this study. Samples were randomly distributed at www.randomizer.org into two groups (n=10) based on the us
group I (GI): Well Root PT (Vericom, Gangwon-Do, Korea), and group II (GII): MTA Biorep (Itena Clinical, Paris, France). Treatment was conducted according to the American Association of Endodontics gu

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients are free from any systemic diseases that may hinder the normal healing process 2. Non-vital permanent anterior teeth with open apex and apical periodontitis 3. Single-rooted teeth 4. The tooth does not require post and core for the final restoration 5. Age range from 9-25 years old

Exclusion criteria

Exclusion criteria: 1. Tooth with vital pulp or complete root formation 2. Tooth with previous endodontic treatment 3. Patients allergic to the medications and antibiotics necessary to complete the treatment 4. Un-cooperative patients

Design outcomes

Primary

MeasureTime frame
The degree of success is measured using the American Association of Endodontists' criterion at baseline and 12 months

Secondary

MeasureTime frame
The following secondary outcome measures were assessed at baseline and 12 months: 1. Pain on biting is measured by asking the patient if it is present or absent 2. Pain on percussion is measured by tapping the tooth with a mirror 3. Soft tissue swelling is measured using visual examination 4. Sinus tract is measured using visual examination 5. Mobility is measured by applying pressure with two metal instruments 6. Pulp sensitivity is measured using Ethyl Chloride spray 7. Root length is measured radiographically using Image J software 8. Root thickness is measured radiographically using Image J software 9. The area of the periapical lesion is measured radiographically using Image J software

Countries

Syria

Contacts

Public ContactAlaa;Alaa Shaker;Shaker

;

alaa1.shaker@damascusuniversity.edu.sy;dr.alaashaker@gmail.com+963949826303;+963949826303

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026