Carbetocin versus oxytocin for the prevention of post-partum hemorrhage in caesarean section

Carbetocin versus oxytocin for the prevention of post-partum hemorrhage in caesarean section: a randomised controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN69805695

Enrollment

Registered

2016-04-20

Start date

2015-01-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Third stage of labour Pregnancy and Childbirth

Interventions

64 pregnant women who had undergone cesarean delivery were randomized into two groups. One group of patients received intravenous 100 microgram carbetocin and another group of patients received intram

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women with a single pregnancy undergoing cesarean delivery at term

Exclusion criteria

Exclusion criteria: 1. Placenta praevia 2. Multiple gestations 3. Placental abruption 4. Hypertensive disorders in pregnancy 5. Preeclampsia 6. Cardiac, renal or liver diseases 7. Epilepsy 8. Women with history of hypersensitivity to carbetocin according to the Br National Formulary

Design outcomes

Primary

Measure	Time frame
Efficacy of carbetocin over oxytocin for the management of third stage of labor	—

Secondary

Measure	Time frame
1. The need for additional uterotonic within 24 hours of delivery after carbetocin or oxytocin administration 2. The amount of blood loss in 24 hours after delivery after carbetocin or oxytocin administration 3. The need for blood transfusion during the first 24 hours after delivery after carbetocin or oxytocin administration 4. The adverse effects of carbetocin and oxytocin after administration	—

Countries

Bangladesh

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026