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In vivo materno-fetal fatty acid transfer in normal and obese pregnancy

In vivo materno-fetal fatty acid transfer in normal and obese pregnancy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN69794527
Enrollment
20
Registered
2017-12-12
Start date
2013-05-13
Completion date
Unknown
Last updated
2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity Nutritional, Metabolic, Endocrine Obesity

Interventions

Ten obese and ten normal weight pregnant women (control) received orally 13C-labelled fatty acids 12h before elective caesarean section: oleic acid, linoleic acid and docosahexaenoic acid. Maternal pl

Sponsors

Commission of the European Communities
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Singleton pregnancy 2. Age 18-40 years 3. Plan to undergo elective caesarean section at term 4. Omnivorous diet 5. No DHA supplements (last trimester) 6. Non-smoking 7. Normal fetal Doppler scan within the normal reference range (24) on the day before caesarean section

Exclusion criteria

Exclusion criteria: Any health problem of the mother or fetus, diabetes, gestational diabetes, preeclampsia

Design outcomes

Primary

MeasureTime frame
13C-enrichment and 13C-fatty acid concentrations in samples of plasma, placenta and cord blood, measured by gas chromatography combustion isotope ratio mass spectrometry at baseline and during the 12h before the cesarean section

Secondary

MeasureTime frame
13C-enrichment and 13C-fatty acid concentrations in maternal plasma lipoproteins, measured by gas chromatography combustion isotope ratio mass spectrometry at baseline and during the 12h before the cesarean section

Countries

Germany, Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 3, 2026