Topic: Primary Care Research Network for England
Conditions
Interventions
Patients that consent and are eligible will be randomised between the intervention arm and standard care.
CRP Test, Patients will receive a finger prick in order to obtain a blood sample for a C-Reac
Sponsors
University of Oxford (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Participant/parent or guardian is willing and able to give informed consent for participation in the study. 2. Male or Female, aged 1 month to 16 years. 3. Presenting to out-of-hours with an acute illness of a maximum of 5 days. 4. A subset of children, i.e. Those with a body temperature >=38°C, will be randomised to CRP or no CRP testing.
Exclusion criteria
Exclusion criteria: 1. Acute trauma 2. Clinically unstable warranting immediate care 3. Prior inclusion in the study 4. Prior inclusion in another clinical trial of an investigational medicinal product in the last 90 days or any other research in the last 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recruitment Rate; Timepoints: Recruitment rate of children to the study over the length of the trial, approximately 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Difference in antibiotic prescription rates. 2. Difference in referrals. 3. Difference in additional testing rates. 4. Difference in hospital admission. 5. Acceptability of the blood test by children and their parents/guardians. 6. Feasibility of the blood test by a nurse. 7. Impact of the blood test on the GPs diagnostic certainty. 8. Impact of the vital signs measurements applied on percentiles and prediction score on GPs diagnostic certainty. | — |
Countries
United Kingdom
Outcome results
None listed