Detecting chronic liver disease using transient elastography

Community-based cluster randomized controlled trial using transient elastography in detecting chronic liver disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN69297334

Enrollment

13350

Registered

2015-12-15

Start date

2013-07-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver disease Digestive System 1. Liver cirrhosis 2. Fatty liver

Interventions

The liver cancer screening conducted by participating health centres are randomly allocated to one of two groups: Group 1: Abdomen screened using Transient elastography plus abdominal ultrasonograph

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 40 and over 2. No severe chronic diseases 3. Have been invited and attended a multiple screening program in Changhua, Taiwan

Exclusion criteria

Exclusion criteria: 1. Those who have hepatocellular carcinoma (HCC) or other severe chronic diseases

Design outcomes

Primary

Measure	Time frame
1. Incidence of HCC or related liver disease is determined using the Taiwanese Cancer Registry and National Mortality Registry at 5 and 10 years post scanning examination 2. Mortality rates are measured using the Taiwanese National Mortality Registry at 5 and 10 years post scan	—

Secondary

Measure	Time frame
Detection rates of liver fibrosis and softness using transient elastography plus abdominal ultrasonography compared with ultrasonography only following completion of the scanning examination.	—

Countries

Taiwan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026