Analysis of heart muscle shape using cardiovascular magnetic resonance imaging

Quantification of myocardial strain assessed by Cardiovascular Magnetic Resonance feature tracking in healthy subjects – influence of post-processing

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN69274813

Enrollment

Registered

2019-11-27

Start date

2013-01-01

Completion date

Unknown

Last updated

2021-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial strain in healthy volunteers Circulatory System Myocardial strain in healthy volunteers

Interventions

The researchers screened healthy subjects, who were prospectively examined in former studies. The ethical committee Charite approved all of the studies. All participants were enrolled after informed c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy male and female aged > 18 years 2. Preserved left ventricular ejection fraction in echocardiography 3. Willingness to undergo CMR 4. Willingness and ability to follow directions and complete all study procedures as specified in the protocol

Exclusion criteria

Exclusion criteria: 1. Any known cardiovascular risk factor 2. History of cardiac disease 3. Impaired LV ejection fraction (LVEF) (< 55%) 4. Pathologic findings in CMR 5. Incomplete CMR data for feature tracking analysis (less than three long axis and three short axis views) led to exclusion

Design outcomes

Primary

Measure	Time frame
1. Longitudinal strain assessed in three long-axis views: 4CV, 3CV and 2CV 2. Circumferential strain and radial strain assessed short-axis full coverage Measured using CMR at a single timepoint	—

Secondary

Measure	Time frame
There were no secondary outcome measures	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026