The iso-volume pressure support range: stable tidal volume conceals major physiological changes during pressure support ventilation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN69141246

Enrollment

Registered

2026-06-30

Start date

2018-09-01

Completion date

Unknown

Last updated

2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients invasively ventilated in pressure-support mode Other

Interventions

A decremental pressure support titration is performed with steps of 2 cmH2O, each lasting five minutes, from 20 to 4 cmH2O. Sedation and analgesia levels are not modified during the titration. PEEP, F

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Adult (age at least 18 years) 2. Invasively ventilated in pressure support mode

Exclusion criteria

Exclusion criteria: 1. Contra-indication to electrical impedance tomography 2. Pregnancy 3. Legal protection status 4. Refusal of the patient or next of kin

Design outcomes

Primary

Measure	Time frame
Tidal Volume measured using data collected from the ventilator screen at the decremental pressure support titration	—

Countries

France

Contacts

Public ContactSamuel Tuffet

stuffet@saintjosephsaintluc.fr+33478618210

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jul 23, 2026