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Eye movement training in visual field defect patients by using a 3D game

Examination of brain plasticity through structural and functional MRI during the audio-visual training in hemianopia patients with virtual reality (VR)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN69117496
Enrollment
30
Registered
2022-11-14
Start date
2024-04-29
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemianopia (partial or complete) Nervous System Diseases

Interventions

The study is designed to present visual stimulus sequences that replicate a conventional visual search scanning with additional audio cues to simulate real-life environments and turn the task into a ‘

Sponsors

University of Liverpool
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Participants are required to be residual homonymous hemianopia (partial or complete following stroke. 2. Participants must have normal hearing and no speaking/communication difficulty. 3. Participants must speak English fluently - in order to understand all training and test instructions. 4. Participants must be 18 years or older. 5. Participants must be able to perform the behavioural tasks, for which training will be provided. 6. Participants must be sufficiently mobile to attend scanning at the imaging centre/LiMRIC

Exclusion criteria

Exclusion criteria: 1. Participant who cannot sign the consent form or cannot read the participants’ information sheet and consent form. 2. Participants who cannot perform the task (the screening takes place before participants are invited to join the study to ensure that, participants can perform the task and to exclude vulnerable adults). 3. MR exclusion criteria: Standard MR exclusion criteria will apply (e.g. claustrophobia (fear of tight spaces), cardiac pacemaker, metal in the eye, vascular clips, actual or possible pregnancy). 4. COVID-19 check: if the participant has any symptoms before the first visit to LiMRIC for the MRI scan and before the training starts (Cough, fever, loss or change in the smell or taste https://www.nhs.uk/conditions/coronavirus-covid-19/symptoms/#symptoms), there is a flexibility to delay the starting of study, but this delaying can not be offer after the study is started. they will be excluded. We will be followed the COVID-19 procedure for LiMRIC at the recruitment period.

Design outcomes

Primary

MeasureTime frame
1. Mean response time and number of correct targets measured using a VR headset during the 30-minute daily sessions, 5 days a week and for 6 consecutive weeks 2. Mean response time and number of correct targets measured in the Digital VISION search at baseline and post training

Secondary

MeasureTime frame
1. Mean response time will be measured in Bell task at baseline and post training. 2. Brain activity and connectivity will be observed using MRI scanning at baseline and post training.

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026