A study to compare the effect of ankle nerve block versus popliteal sciatic nerve block on pain following forefoot surgery

Ankle nerve block versus popliteal sciatic nerve block in ambulatory surgery after forefoot surgery (PSNSB-ANB-RCT): an RCT and follow-up study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN69106683

Enrollment

220

Registered

2022-08-08

Start date

2022-08-15

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Management of pain in patients undergoing forefoot surgery. Surgery

Interventions

Patients will receive either an ultrasound-guided ankle block (group A) or an ultrasound-guided popliteal sciatic nerve block with n. saphenous block (group B) combined with standardized anesthesia an

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Scheduled for ambulatory metatarsal osteotomy/forefoot surgery 2. American Society of Anesthesiologist (ASA) physical status I-II 3. Provides written informed consent 4. Good understanding of the Dutch language 5. Aged =18 years 6. Without premedication

Exclusion criteria

Exclusion criteria: 1. Refusal to participate 2. Aged ?18 years 3. Known preexisting neuropathies 4. Known impaired cognitive function 5. Systemic glucocorticoid administration 6. Pregnancy 7. Chronic use of opioids 8. Intolerance for local anesthetics and non-steroidal anti-inflammatory drugs (NSAID) 9. Revision surgery

Design outcomes

Primary

Measure	Time frame
Pain measured using the Visual Analogue Scale – Pain (VAS-P) between 0 and 7 days postoperatively and at 14 days postoperatively	—

Secondary

Measure	Time frame
1. Functional recovery measured using the Functional Recovery Index (FRI) at 7 and 14 days postoperatively 2. Effective duration of analgesia of locoregional block measured using a Visual Analogue Scale – Pain (VAS-P) and noted in the patient’s diary on the day of surgery 3. Participants’ subjective satisfaction with placement of the regional block measured using a four-point Likert scale on the day of surgery 4. Pain medication adherence at home measured using participant diaries between 0 and 7 days postoperatively 5. Adverse effects including abnormal proprioception, numbness, paraesthesia, neuralgia, or motor weakness measured using participant diaries between 0 and 7 days postoperatively and at 14 days postoperatively	—

Measure

Time frame

1. Functional recovery measured using the Functional Recovery Index (FRI) at 7 and 14 days postoperatively 2. Effective duration of analgesia of locoregional block measured using a Visual Analogue Scale – Pain (VAS-P) and noted in the patient’s diary on the day of surgery 3. Participants’ subjective satisfaction with placement of the regional block measured using a four-point Likert scale on the day of surgery 4. Pain medication adherence at home measured using participant diaries between 0 and 7 days postoperatively 5. Adverse effects including abnormal proprioception, numbness, paraesthesia, neuralgia, or motor weakness measured using participant diaries between 0 and 7 days postoperatively and at 14 days postoperatively

—

Countries

Belgium

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026