Physiological gingival pigmentation Postoperative healing after depigmentation surgery Oral Health
Conditions
Interventions
Healthy adult participants aged 18–40 years with bilateral physiological gingival pigmentation in the upper anterior region were enrolled after providing written informed consent. Each participant und
Sponsors
Damascus University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18–40 years 2. Presence of physiological melanin pigmentation in the upper anterior gingiva (Hedin index 3 or 4) 3. Confirmed absence of systemic or pathological causes of pigmentation 4. Good general health (ASA I) 5. Adequate width and thickness of attached gingiva 6. No signs of active periodontal disease 7. No prior surgical intervention in the target area 8. Informed consent provided and willingness to comply with follow-up visits
Exclusion criteria
Exclusion criteria: 1. Smoking or tobacco use 2. Alcohol abuse 3. Pregnancy or lactation 4. Use of anti-inflammatory, immunosuppressive, or photosensitizing medications 5. Systemic diseases affecting healing (e.g. uncontrolled diabetes) 6. History of radiation therapy 7. Known allergy to any component of benzoin resin tincture or Coe-Pak dressing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Epithelialization index measured using the degree of epithelial coverage at the surgical site (Grade 0–3), weekly for 4 weeks postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Healing measured using the Wound Healing Index (H1–H5) assessed weekly for 4 weeks 2. Pain measured using a Visual Analog Scale (VAS ) daily from Day 1 to Day 7 3. Rescue medication usage measured using the number of analgesic tablets consumed over 7 days | — |
Countries
Syria
Contacts
Public ContactTala Alkhin Alkhin
Outcome results
None listed