Specialty: Cancer, Primary sub-specialty: Gynae
Conditions
Interventions
Current interventions as of 08/09/2017:
Before their colposcopy examination women, who have signed a consent form to take part, will firstly be asked to provide a sample of urine using
Sponsors
Bart’s Health NHS Trust
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women attending for colposcopic examination at the Royal London Hospital colposcopy clinic 2. Referred as a consequence of abnormal screening cytology and/or positive HPV result 3. Who have a cervix 4. Who give written informed consent 5. Aged 18 years and above
Exclusion criteria
Exclusion criteria: 1. Pregnancy 2. History of excisional or ablative treatment for CIN within the last three years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The total amount of nucleic acid in the samples (including RNA) 2. Quantification of amplifiable human genomic DNA 3. Estimation of the viral load of HPV16 in the samples 4. Validated HPV platforms which will give quantifiable measures of HPV with some degree of typing | — |
Secondary
| Measure | Time frame |
|---|---|
| Histological and cytological outcomes and total scores allocated by women to each test on the acceptability questionnaire | — |
Countries
England, United Kingdom
Contacts
Public ContactLouise Cadman
Outcome results
None listed