Crohn's disease Digestive System Crohn disease, unspecified
Conditions
Interventions
This will be a randomised controlled study. Patients will be enrolled for the study preoperatively. Patients will be invited to participate at the first available opportunity following the decision to
Sponsors
St George's University of London (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with histological diagnosis of Crohn's disease 2. Patients who needed surgery for Crohn's disease 3. Patients who agreed to dietary therapy for a minimum of 1 year or until relapse 4. Patients aged 16 and over 5. Patients capable of providing informed consent
Exclusion criteria
Exclusion criteria: 1. Severe disease unrelated to Crohn's disease like chronic renal failure or chronic liver disease or immunological disorders 2. Disease localised perineum 3. Other inflammatory conditions of bowel including Ulcerative colitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Relapse over a 1 year period defined by Rutgeerts endoscopic severity score of i2, i3 or i4 2. Crohn's Disease Activity Index (CDAI) >150 or CDAI increase of more than 100 over baseline 3. Need for therapy to induce remission | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in quality of life, measured by Short Inflammatory Bowel Disease Questionnaire (SIBDQ) | — |
Countries
United Kingdom
Outcome results
None listed