Magnetic Sentinel Node and Occult Lesion Localisation (MagSNOLL)

Magnetic Sentinel Node and Occult Lesion Localisation: A feasibility study using magnetic nanoparticles for sentinel node biopsy and localisation of occult breast cancers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN68689512

Enrollment

Registered

2013-09-10

Start date

2013-08-07

Completion date

Unknown

Last updated

2017-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: National Cancer Research Network

Interventions

Injection of magnetic dye, Intra-tumoral injection of 0.5 mL magnetic dye (Sienna+) Follow Up Length: 12 months

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Patients with operable breast cancer visible on ultrasound and suitable for SLNB 2. Neoadjuvant chemotherapy sub-protocol: Patients with breast cancer due to undergo neoadjuvant chemotherapy and post-chemotherapy SLNB 3. Target Gender: Female ; Lower Age Limit 18 years

Exclusion criteria

Exclusion criteria: 1. Intolerance / hypersensitivity to iron or dextran compounds or Sienna + 2. Patients who cannot / do not receive radioisotope for SLNB 3. Patients with an iron overload disease 4. Patients with pacemakers or other implantable devices in the chestwall

Design outcomes

Primary

Measure	Time frame
Successful sentinel lymph node biopsy and lesion localisation.	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026