Whiplash cervical injuries Injury, Occupational Diseases, Poisoning Injuries to the neck
Conditions
Interventions
Randomised, prospective, double blind, placebo-controlled study comparing Botox® with placebo.
The study evaluates the efficacy and safety of Botox® in patients with musculoskeletal pain after whipl
Sponsors
Povisa Medical Center (Povisa Centro Medico) (Spain)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with grade II Whiplash Associated Disorders (WAD) of Quebec Task Force (QTF)-WAD 2. Neck pain secondary to cervical whiplash injury with musculoskeletal signs of greater than three months 3. Aged greater than 18 years 4. Lack of response to conventional physical and medical therapy Musculoskeletal signs: 1. Palpable band, spot tenderness, and jump sign in cervical muscles or restricted range of motion in cervical spine 2. Demonstrated precipitation of neck pain with external pressure over the occipital or cervical region on affected side 3. Myofascial pain of cervical muscles 4. Experienced pain on maneuver of stretching 5. Trigger point with associated referred pain
Exclusion criteria
Exclusion criteria: 1. Serious somatic or psychiatric illness 2. Anticoagulation therapy 3. Myasthenia gravis 4. Pregnancy or breast-feeding 5. Abnormal anatomy 6. Rheumatoid disease or radiculopathy 7. Need for regular analgesic for severe pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
Spain
Outcome results
None listed