Impact of disease burden and setting-specific interventions on schoolchildren?s cardio-respiratory physical fitness and psychosocial health in Port Elizabeth, South Africa

Conditions

Communicable diseases (e.g. intestinal protozoa and helminth infections) and non-communicable chronic conditions (e.g. type 2 diabetes and malnutrition) Infections and Infestations

Ivan Müller, Cheryl Walter, Rosa du Randt, Ann Aerts, Larissa Adams et al. (18 authors)

BMJ Open Sport & Exercise Medicine2020-09-0114 citations

10.1136/bmjsem-2020-000823

Associations between selective attention and soil-transmitted helminth infections, socioeconomic status, and physical fitness in disadvantaged children in Port Elizabeth, South Africa: An observational study

Stefanie Gall, Ivan Müller, Cheryl Walter, Harald Seelig, Liana Steenkamp et al. (15 authors)

PLoS neglected tropical diseases2017-05-0849 citations

10.1371/journal.pntd.0005573

Disease, activity and schoolchildren's health (DASH) in Port Elizabeth, South Africa: a study protocol.

Yap P, Müller I, Walter C, Seelig H, Gerber M, Steinmann P, Damons BP, Smith D, Gall S, Bänninger D, Hager T, Htun NS, Steenkamp L, Gresse A, Probst-Hensch N, Utzinger J, Du Randt R, Pühse U.

2015-12-2318 citations

10.1186/s12889-015-2636-y

Interventions

The following intervention toolbox is proposed but the specific combination of interventions to be used will be governed by the key findings from the initial cross-sectional baseline survey: Physical

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Willing to participate in the study 2. Be in possession of a written informed consent by a parent/guardian on behalf of the child 3. Not participating in other studies 4. Being a primary school child aged 9-12 years, male or female 5. Absence of ill-health condition (e.g. severe anaemia, respiratory disease or other major illnesses), as assessed by a medical doctor at baseline.

Exclusion criteria

Exclusion criteria: 1. Children below the age of 9 years or above 12 years 2. Not having a written informed consent or no parental/legal guardian?s permission to participate 3. Suffer from medical conditions which prevent participation in the study, as determined by qualified medical personnel 4. Attending other clinical trials during the study period.

Design outcomes

Primary

Measure	Time frame
1. The prevalence of communicable diseases (e.g. intestinal protozoa and helminth infections) and non-communicable chronic conditions (e.g. type 2 diabetes and malnutrition). 2. Differences (non-infected vs. infected) and changes (before and after treatment) in physical fitness levels, psychosocial health and cognitive performance.	—

Secondary

Measure	Time frame
1. Reduction of infection prevalence and intensity of soil-transmitted helminths and schistosomiasis. 2. Differences and changes in disease-related morbidity measures (malnutrition and anaemia). Treatment will be administered to all study participants directly after baseline assessments, 1 year and 2 years after baseline. Reassessment of parasitic infection, anthropometric and haemoglobin measurements, clinical examination, physical fitness and cognitive performance will take place at the end of the study follow-up, 2 years after baseline.	—

Measure

Time frame

1. Reduction of infection prevalence and intensity of soil-transmitted helminths and schistosomiasis. 2. Differences and changes in disease-related morbidity measures (malnutrition and anaemia). Treatment will be administered to all study participants directly after baseline assessments, 1 year and 2 years after baseline. Reassessment of parasitic infection, anthropometric and haemoglobin measurements, clinical examination, physical fitness and cognitive performance will take place at the end of the study follow-up, 2 years after baseline.

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Countries

South Africa

Outcome results

None listed