Central Venous Catheter Associated Infections Infections and Infestations Catheter infections
Conditions
Interventions
There are two parts to the study:
In part one, we will determine how a novel molecular test for the diagnosis of CVC-associated infections performs in children being treated for cance
Sponsors
Department of Health (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Child, adolescent or young adult aged zero 18 years inclusive 2. Undergoing treatment for cancer/leukaemia or severe haematological disorders at a collaborating United Kingdom Children's Cancer Study Group (UKCCSG) centre 3. The routine standard of care requires a tunnelled single, double or triple lumen CVC or implanted vascular port 4. It is expected that the CVC or port will be required for a minimum of three months 5. Patients who already have an indwelling vascular access device in situ at the time of recruitment are eligible if they have been apyrexial and have not received intravenous antimicrobial therapy in the preceding two weeks 6. Written informed consent has been obtained from the parent/guardian and assent from the patient where appropriate 7. National/Local Ethical Committee approval has been obtained
Exclusion criteria
Exclusion criteria: 1. Failure to meet the above criteria 2. Patients with untunnelled CVCs or short term CVCs will not be included
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1. Duration of antibiotic treatment and hospitalisation for fever 2. Mortality 3. Economic analysis | — |
Primary
| Measure | Time frame |
|---|---|
| CVC survival | — |
Countries
England, United Kingdom
Outcome results
None listed