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Is repeated laser treatment effective in intraocular pressure (IOP) reduction?

Intraocular pressure reduction after repeated selective laser trabeculoplasty (SLT): A prospective randomised clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN67927615
Enrollment
40
Registered
2010-03-16
Start date
2010-02-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma Eye Diseases Glaucoma

Interventions

Patients will be treated with SLT 2 and randomly divided to treatment in adjacent place (classically treated) or in the same place. Then will be checked at 1 month, 3 months, 6 months and 12 months af

Sponsors

St Eriks Eye Hospital (Sweden)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients suffering from glaucoma or Ocular Hypertenstion (OHT) 1.1. Primary open angle glaucoma (POAG) - open angle defined as > grade II (Shaffer classification: scale 0-IV) assessed by gonioscopy 1.2. Pigmentary and pseudoexfoliative glaucoma 1.3. OHT to be treated with SLT 2 both with and without eye-drops. 2. If both eyes must be treated just one will be selected at random. 3. Older than 18 years, no upper age limit 4. Men and women

Exclusion criteria

Exclusion criteria: 1. Patients treated with cortisone or immunosuppressive drugs 2. Patients suffering from ocular or systemic inflammatory diseases 3. Patients with Possner-Schlossman syndrome 4. Patients that cannot be treated with SLT due to eye?s characteristics (shallow anterior chamber) or bad collaboration

Design outcomes

Primary

MeasureTime frame
IOP after repeated SLT in the same area against repeated SLT treatment in adjacent areas. IOP will be measured with the Goldmann applanation tonometry (GAT) at base line (before treatment) and then 1, 3, 6 and 12 months after treatment.

Secondary

MeasureTime frame
1. Gender?s influence on IOP 2. Age?s influence on IOP 3. Pseudoexfoliation?s influence on IOP 4. Inflammation measurements using a slit-lamp and according to the international classification of the Standardization of Uveitis Nomenclature (SUN) Working Group

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026