TRansvaginal Ultrasonography versus Saline sonography Trial in patients having their IVF treatment - TRUST-IVF study

A randomised controlled trial comparing Transvaginal Ultrasonography versus Saline sonography Trial in patients having their IVF treatment - TRUST-IVF study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN67886141

Enrollment

792

Registered

2012-08-16

Start date

2012-07-01

Completion date

Unknown

Last updated

2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

In vitro fertilisation (IVF) Pregnancy and Childbirth In vitro fertilization

Interventions

All women recruited for the trial will undergo a 2-D TVS. If the initial scan is normal, the participants will then undergo randomisation to receive SIS or another 2-D TVS before commencing their trea

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Women undergoing their first and second IVF/ ICSI (Intra Cytoplasmic Sperm Injection) treatment 2. Women under the age of 40 and undergoing their first or second IVF cycle will be eligible to participate in the trial

Exclusion criteria

Exclusion criteria: 1. Women aged more than 40 years (women aged 41 years or more). 2. Known submucous fibroids, polyps, intrauterine adhesions or uterine surgery 3. Untreated Hydrosalpinges (women whose hydrosalpinges have been treated with clipping, salpingectomy or ligation will be included) 4. Recurrent implantation failure defined as patients undergoing three or more IVF cycles

Design outcomes

Primary

Measure	Time frame
Livebirth rate	—

Secondary

Measure	Time frame
1. Clinical pregnancy rate 2. Implantation rate 3. Uterine anomaly rate	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026