Non-cardiac chest pain patients with a diagnosed panic and/or depressive disorder Mental and Behavioural Disorders Depressive episode, unspecified
Conditions
Interventions
Patients randomized to TAU are reassured by the cardiologist that their complaints were not caused by cardiac disease. TAU is tailored to the individual needs of the patients. However, TAU does not in
Sponsors
VU University Medical Center (Netherlands)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. All subjects aged 18 years or older who present themselves at the cardiac emergency unit of the VU University Medical Center with chest pain and are convinced they are experiencing a heart attack. 2. Full medical examination reveals no cardiopulmonary, gastrointestinal or endocrinal explanation for their complaints (and thus were diagnosed with 'non-cardiac chest pain') 3. Score 8 or higher on either or both subscales of the Hospital Anxiety and Depression Scale (HADS). 4. Meeting the DSM-IV criteria for panic disorder and/or depressive disorder 5. Providing signed informed consent after an oral and written explanation of the procedures and purpose of the study
Exclusion criteria
Exclusion criteria: 1. Those with insufficient knowledge of the Dutch language 2. Those who, in the month before screening, received systematic psychotherapy or used antidepressants. Benzodiazepine usage is allowed during the trial, up to a maximum of 50 mg of oxazepam or equivalent doses of other medications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease severity with the Clinical Global Inventory (CGI) by a blinded independent rater. | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety and depressive symptoms as assessed with the State-Trait Anxiety Inventory, the Fear Questionnaire, the Hospital Anxiety and Depression Scale and the Hamilton Depression Rating Scale. Furthermore, in the completer sample, at 24 weeks the assessor-rated Clinical Global Impression-Improvement Scale (CGI-Improvement) is administered. | — |
Countries
Netherlands
Outcome results
None listed