Periodontitis Oral Health
Conditions
Interventions
Randomisation was performed by tossing a coin before the intervention. Patients were randomly assigned to two groups:
1. The study group (SRP + local antibiotic application to pockets minimum 5 mm)
2.
Sponsors
Medical University of Bialystok
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed periodontitis stage II or III, grade B or C 2. Presence of at least 16 teeth (at least 4 in each quadrant) 3. Presence of at least 4 deep periodontal pockets (PD =5 mm) 4. No professional hygiene procedures in the last 6 months 5. No systemic antibiotic therapy in the last 3 months 6. Aged over 18 years 7. Being non-smoker
Exclusion criteria
Exclusion criteria: 1. General contraindications to any periodontal therapy 2. Immunosuppression 3. Immunological incompetence 4. Uncontrolled diabetes 5. Pregnancy and breastfeeding 6. Alcohol and/or drug dependence 7. Patient allergic to any antibiotics 8. Patient requiring antibiotic cover prior to periodontal therapy 9. Patient with no opportunity to participate in the programme for 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Pocket depth (PD) measured in mm with periodontal probe PCUNC15 at baseline, 3 and 6 months 2. Clinical attachment level (CAL) measured in mm with periodontal probe PCUNC15 at baseline, 3 and 6 months 3. Gingival recession (GR) measured in mm with periodontal probe PCUNC15 at baseline, 3 and 6 months 4. Number of pockets with PD >=5 mm counted at baseline, 3 and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Gingival crevicular fluid (GCF) sampled at baseline, 2 weeks, 3 months and 6 months and frozen for future laboratory analysis | — |
Countries
Poland
Contacts
Public ContactEwa Dolinska
Outcome results
None listed