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Developing an intervention to improve paediatric HIV care in central Mozambique

Reducing loss-to-follow-up among HIV-exposed infants in Central Mozambique: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN67747315
Enrollment
150
Registered
2019-07-25
Start date
2015-12-21
Completion date
Unknown
Last updated
2020-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV disease Infections and Infestations Human immunodeficiency virus [HIV] disease

Interventions

The intervention was developed following the initial formative research phase. The formative research phase includes patient flow mapping, focus group discussions with patients and health workers, and

Sponsors

Centro de Investigação Operacional Da Beira
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Clinics: 1. High patient volume in antenatal care (ANC). 2. High HIV prevalence in ANC. 3. Already implementing Option B+ (HIV test and treat for pregnant mothers). 4. Located along the Beira highway corridor to assure access. Health workers: 1. Providers of post-partum, child-at-risk, and ART services at each clinic. Mothers: 1. Active women members of HIV-positive members at each clinic site. 2. HIV-positive Women, age 18-44. 3. Patient at a local clinic.

Exclusion criteria

Exclusion criteria: N/A

Design outcomes

Primary

MeasureTime frame
Data on all outcomes are gathered at 3-month intervals at each of the six clinics, beginning at baseline (3 months before the intervention began): 1. PCR testing rates among HIV-exposed infants presenting to CCR. 2. The proportion of HIV-exposed infants attending 2 or more CCR visits. 3. The proportion of HIV-exposed infants at CCR receiving cotrimoxazole prophylaxis. 4. The proportion of HIV-positive infants identified via PCR at CCR clinics who enrol in care at an HIV treatment clinic within 45 days of positive test results (known as consulta de TARV, or ART).

Secondary

MeasureTime frame
Data on all outcomes are gathered at 3-month intervals at each of the six clinics, beginning at baseline (3 months before the intervention began): 1. The proportion of caregivers of infants with positive PCR result who are notified of infant’s positive HIV status. 2. The time interval from CCR visit at which PCR test sample obtained to first ART visit for PCR positive infants. 3. The acceptability of EID oriented intervention to healthcare workers and HIV-positive mothers measured using individual interviews, focus group discussions to the mothers and routine data collections.

Countries

Micronesia, Federated States of, Mozambique

Contacts

Public ContactLúcia Da Costa Vieira
luciadacostavieira@gmail.com+258 23324308

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 18, 2026