Halitosis without periodontitis and otolaryngological disease. Ear, Nose and Throat Halitosis
Conditions
Interventions
Participants are randomly allocated into three groups:
1. Test Group: Instructed to gargle with mouthwash containing 0.004% benzethonium chloride and artificial colorants (tartrazine and Brilliant Blu
Sponsors
Aichi Gakuin University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. To have visited the Aichi Gakuin University Dental Hospital and claiming oral malodour 2. No history of antibiotic use within the past 3 months 3. No history of otolaryngology consultation due to sinusitis, tonsillitis and tonsilloliths within the past 3 months
Exclusion criteria
Exclusion criteria: 1) Otolaryngological disease at baseline 2) Periodontitis 3) To have used a gargle on the day of screening 4) A negative result for an organoleptic assessment (score 0) 5) Less than 26 ppb CH3SH in mouth air 6) Score of more than 30% on the Plaque Control Record
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparing the concentrations of VSC's (H2S, CH3SH, and CH3SCH3) in mouth air, measured using OralChroma, and organoleptic score, determined using the Rosenberg’s scale. Outcomes are measured at baseline and after 9 days. | — |
Secondary
| Measure | Time frame |
|---|---|
| Outcomes are measured at baseline and after 9 days: 1. Concentrations of VSCs are measured using OralChroma. 2. Organoleptic assessment is judged on a 0–5 scale (Rosenberg’s scale). 3. Tongue coating score is recorded with Kojima’s scale. 4. Bacterial profiles are assessed by T-RFLP analysis. | — |
Countries
Japan
Contacts
Public ContactMitsuo Fukuda
Outcome results
None listed