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The effect of dexmedetomidine in addition to local anaesthetic on the block of nerves in the arm

Effects of dexmedetomidine addition to levobupivacaine in axillary brachial plexus blockade

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN67622282
Enrollment
64
Registered
2012-02-10
Start date
2011-11-20
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia and analgesia in the arm Surgery

Interventions

The patients were randomly divided into two groups: Group L (n=32): Levobupivacaine (Chirocaine, 5 mg/mL
Abbott Lab/Turkey) with isotonic sodium chloride Group D (n=32): Levobupivacaine and dexmedetomidine (Precedex 200 mcg / 2 mL, Meditera, Turkey) with isotonic sodium chloride

Sponsors

Cumhuriyet University (Turkey)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18-60 2. Male and female participants 3. Scheduled forearm and hand surgery patients

Exclusion criteria

Exclusion criteria: 1. Patients with a history of cardiac, respiratory, hepatic, or renal failure, coagulopathy, and allergy to amid local anesthetics 2. Receiving adrenoreceptor agonist or antagonist therapy, chronic analgesic therapy 3. Pregnant women

Design outcomes

Primary

MeasureTime frame
1. Sensory and motor block onset time, defined as the time between the end of the local anesthetic injection and no response to the pinprick test and complete paralysis 2. Sensory and motor block durations. The duration of sensory block was considered as the time interval between the complete sensory block and the first postoperative pain, and the duration of motor block was defined as the time interval between the complete paralysis and complete recovery of motor function 3. Time to first analgesic use recorded during postoperative first 12 hours

Secondary

MeasureTime frame
1. Mean arterial pressure 2. Heart rate

Countries

Turkey

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 26, 2026