Foods for weight management (Elintarvikkeita painonhallintaan)

Foods for weight management: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN67529475

Enrollment

100

Registered

2014-01-29

Start date

2008-05-01

Completion date

Unknown

Last updated

2023-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity Nutritional, Metabolic, Endocrine Obesity

Interventions

Participants are randomized to two groups: high-satiety and low-satiety food groups All participants will receive a very low calorie diet for 8 weeks. The weight maintenance period is

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Body mass index 30?40 kg/m2 2. Age 30?65 years

Exclusion criteria

Exclusion criteria: 1. BMI >40 or 16, men > 24 portions/week). 9. No other diseases, medications, or life situations that would prevent them from successfully completing the study

Design outcomes

Primary

Measure	Time frame
1. Body weight measured by a digital scale at baseline, 8, 12, 24 weeks and at follow-up.	—

Secondary

Measure	Time frame
1. Anthropometry and body composition: height measured using a wall-mounted stadiometer at screening; waist circumference using a calibrated tape measured at baseline, 8, 12 and 24 weeks; body composition using fat mass and fat-free mass by bioelectrical impedance measured at baseline, 8, 12 and 24 weeks 2. Eating behaviour by questionnaires at baseline, 12 and 24 weeks 3. Glucose and lipid metabolism and satiety-related hormones measured at baseline, 8, 12 and 24 weeks 3.1. Lipid metabolism: fasting serum HDL-, LDL-, total cholesterol, triglycerides and free fatty acids samples 3.2. Glucose metabolism: fasting and 2-hour oral glucose tolerance test (time points 0 min, 30 min, 60 min and 120 min) plasma/serum glucose and insulin samples 3.3. Satiety-related hormones: fasting plasma ghrelin, leptin, peptide YY samples 4. Inflammatory markers: serum/plasma CRP, IL6, IL1ra, adiponectin samples measured at baseline, 8 and 24 weeks 5. Adipose tissue and peripheral blood mononuclear cell gene expression: optional, performed only for those who were willing to give the samples. Measured by adipose tissue biopsies from subcutaneous abdominal fat and peripheral blood mononuclear cells (PBMCs) isolated from anticoagulated peripheral blood samples measured at baseline, 8 and 24 weeks 6. Gut microbiota composition by taking fecal samples measured at baseline, 8 and 24 weeks	—

Measure

Time frame

1. Anthropometry and body composition: height measured using a wall-mounted stadiometer at screening; waist circumference using a calibrated tape measured at baseline, 8, 12 and 24 weeks; body composition using fat mass and fat-free mass by bioelectrical impedance measured at baseline, 8, 12 and 24 weeks 2. Eating behaviour by questionnaires at baseline, 12 and 24 weeks 3. Glucose and lipid metabolism and satiety-related hormones measured at baseline, 8, 12 and 24 weeks 3.1. Lipid metabolism: fasting serum HDL-, LDL-, total cholesterol, triglycerides and free fatty acids samples 3.2. Glucose metabolism: fasting and 2-hour oral glucose tolerance test (time points 0 min, 30 min, 60 min and 120 min) plasma/serum glucose and insulin samples 3.3. Satiety-related hormones: fasting plasma ghrelin, leptin, peptide YY samples 4. Inflammatory markers: serum/plasma CRP, IL6, IL1ra, adiponectin samples measured at baseline, 8 and 24 weeks 5. Adipose tissue and peripheral blood mononuclear cell gene expression: optional, performed only for those who were willing to give the samples. Measured by adipose tissue biopsies from subcutaneous abdominal fat and peripheral blood mononuclear cells (PBMCs) isolated from anticoagulated peripheral blood samples measured at baseline, 8 and 24 weeks 6. Gut microbiota composition by taking fecal samples measured at baseline, 8 and 24 weeks

—

Countries

Finland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026