Malnutrition and HIV infection Infections and Infestations HIV and malnutrition
Conditions
Interventions
375 g CSB (300 g corn and 75 g soy flour fortified with vitamins and minerals), or 260 g peanut-based RUTF (26% dried skimmed milk, 27% sugar, 26% peanut paste, 20% vegetable oil, and 1.5% vitamins) a
Sponsors
St. Louis Children's Hospital (USA)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults (>18 years old) diagnosed with acquired immune deficiency syndrome (AIDS) and meeting eligibility criteria for ART according to the National HIV treatment guidelines 2. World Health Organisation (WHO) stage III or IV or any WHO stage and a CD4 count <200 /mm^3 and beginning treatment with ART with a body mass index (BMI) of <18.5
Exclusion criteria
Exclusion criteria: 1. Age <18 years 2. Pregnant or lactating women 3. Enrolment in any other supplementary feeding program
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body mass index and fat free body mass as measured by the bioelectrical impedance at 3, 6, 9 and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The number and severity of clinical events at 3, 6, 9 and 12 months 2. Monthly change in quality of life assessment 3. The change from baseline in the CD4 count at three months 4. Serum albumin and hematocrit at three months 5. Viral load at three months 6. Compliance with ART regimen 7. Cost-effectiveness of the two dietary regimens | — |
Countries
Malawi
Outcome results
None listed