The potential role of B-Type natriuretic peptide (BNP) and high-sensitivity troponin t(hs-tnt) pre-screening by GPs to better target rapid access chest pain clinic referrals

The potential role of B-Type natriuretic peptide (BNP) and high-sensitivity troponin t(hs-tnt) pre-screening by GPs to better target rapid access chest pain clinic referrals: a prospective observational longitudinal cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN67362546

Enrollment

625

Registered

2010-04-06

Start date

2007-03-01

Completion date

Unknown

Last updated

2017-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac chest pain Circulatory System Angina pectoris

Interventions

625 patients attending Rapid Access Chest Pain Clinics in Tayside were recruited into the study over a two year period. Each patient had demographic data, a near patient BNP and high-sensitivity tropo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients presenting to the rapid Access Chest Pain Clinic with Cardiac Chest Pain 2. Aged 20 - 93 years, both male and female

Exclusion criteria

Exclusion criteria: Patients with non-cardiac chest pain

Design outcomes

Primary

Measure	Time frame
Negative predictive value of BNP compared to final clinical diagnosis and troponin T result is measured by a near-patient assay at 12 months.	—

Secondary

Measure	Time frame
Clinical event rate such as further admissions for chest pain, referral for angioplasty or coronary artery bypass grafting and death are assessed continuously for 12 months.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026