Incontinence following radical prostatectomy for prostate cancer Surgery
Conditions
Interventions
MRT, urodynamics and trans-rectal ultrasound pre-operative and at three months postoperative
The plan of study visits is described below.
VISIT 1
The assessment of eligibility is done by a urologis
Sponsors
University of Gothenburg
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Patients scheduled for robot-assisted laparoscopic radical prostatectomy at Sahlgrenska University Hospital
Exclusion criteria
Exclusion criteria: Pre-operative incontinence
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urethral length, position of prostate apex, position of bladder neck, position of urethra, thickness of urethra, M. levator ani and M. Pubourethralis/puborectalis and signs of fibrosis of urethra wall, assessed by MRT at baseline and 12 weeks (except for prostate apex at 12 weeks) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Clinical characteristics (comorbidity, medications, BMI, smoking, IPSS, PSA, Gleason score and T-stage) assessed at baseline 2. Urethra pressure profile, sphincter length, function of bladder and bladder outflow tract assessed by urodynamics at baseline and 12 weeks 3. Position and movement of bladder neck and pelvic floor at relaxation and full tension of pelvic floor assessed by ultrasound at baseline and at 12 weeks. 4. Steps of surgery and potential damage of structures around sphincter assessed by video recording at time of surgery | — |
Countries
Sweden
Outcome results
None listed