Comparison of two modalities of aerobic training on health-parameters in adolescent obese

Microvascular adaptations after moderate continuous and high-intensity interval-training in adolescents with severe obesity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN67155720

Enrollment

Registered

2016-02-16

Start date

2013-01-30

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity Nutritional, Metabolic, Endocrine

Interventions

At the start of the study, the cutaneous microvascular function of all participants are assessed. Obese adolescents also undergo body composition, metabolic profile and aerobic fitness assessments. T

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Obese adolescents, male or female, aged 12-16 years, non-smokers, not taking any medications and without known cardiovascular or metabolic disease 2. Healthy normal-weight pubertal stage-matched adolescents

Exclusion criteria

Exclusion criteria: 1. Smokers 2. Adolescents who participated in extra-school sport activities more than 2h per week

Design outcomes

Primary

Measure	Time frame
Cutaneous blood flux (CBF) was determined by means of laser Doppler flowmetry (Periflux PF 5000, Perimed, Stockholm, Sweden) equipped with a thermostatic LDF probe (PF 481, Perimed, Stockholm, Sweden), on the volar surface of the right forearm. Assessed at baseline in obese adolescents and controls, and after 3 months of intervention only in obese adolescents.	—

Secondary

Measure	Time frame
1. Body composition, assessed only in obese adolescents at inclusion and after 3 months of intervention 2. Aerobic fitness (including the 20-meter shuttle run test), assessed only in obese adolescents at inclusion and after 3 months of intervention 3. Weight and height measurements were performed and body mass index (BMI) was calculated as weight in kilograms divided by height in squared meters (kg.m-2), at baseline and after 3 months of intervention 4. Body fat mass, abdominal and gluteal fat masses and lean body mass, assessed in only obese adolescents using dual-energy X-ray absorptiometry (DEXA), (QDR 2000 – Discovery, Hologic, Bedford, MA), at baseline and after 3 months of intervention 4. Plasma glucose, plasma insulin and lipid profile were assessed only in obese adolescents using fasting blood samples, at baseline and after 3 months of intervention	—

Measure

Time frame

1. Body composition, assessed only in obese adolescents at inclusion and after 3 months of intervention 2. Aerobic fitness (including the 20-meter shuttle run test), assessed only in obese adolescents at inclusion and after 3 months of intervention 3. Weight and height measurements were performed and body mass index (BMI) was calculated as weight in kilograms divided by height in squared meters (kg.m-2), at baseline and after 3 months of intervention 4. Body fat mass, abdominal and gluteal fat masses and lean body mass, assessed in only obese adolescents using dual-energy X-ray absorptiometry (DEXA), (QDR 2000 – Discovery, Hologic, Bedford, MA), at baseline and after 3 months of intervention 4. Plasma glucose, plasma insulin and lipid profile were assessed only in obese adolescents using fasting blood samples, at baseline and after 3 months of intervention

—

Countries

France

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026