Multiple sclerosis Nervous System Diseases Multiple sclerosis
Conditions
Interventions
Pilot study: participants will be randomly allocated to one of three groups (below)
Main study: there will be a specific allocation to groups (stratified block randomisation)
Group A: guided motor im
weekly change of Audio-Mix provided by a CD designed for this study. Detailed instructions.
Group B: guided motor imagery plus metronome cues, weekly phone calls for support. Same procedure.
Group
Sponsors
Innsbruck Medical University (Austria)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. People with mild MS (Expanded Disability Status Scale, EDSS 1.5 to 4.5) 2. Aged 18 years or over 3. Clinical MS according to McDonald's criteria as diagnosed by Innsbruck MS Clinics 4. All MS phenotypes 5. Any ethnicity 6. German speaking
Exclusion criteria
Exclusion criteria: 1. Concomitant other diseases which are affecting rhythmic cued motor imagery and walking (e.g., hearing impairment) 2. A relapse of MS within the last 3 months 3. Known pregnancy 4. Any cognitive deficits or depression, diagnosed and documented by the MS Clinics in Innsbruck 5. A relapse during the intervention period will lead to exclusion of the participant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in walking measured by the Timed 25-Foot Walk (T25FW) and 6-Minute Walk Test (6MWT). Assessments will be taken at the start and after 4 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of: 1. Walking (MS Walking Scale-12, MSWS-12) 2. Fatigue (Modified Fatigue Impact Scale, MFIS) 3. Quality of life (MS Impact Scale-29, MSIS-29) 4. Health-related quality of life (Short-Form Health Survey-36, SF-36, EQ-5D-3L) Assessments will be taken at the start and after 4 weeks. | — |
Countries
Austria
Outcome results
None listed