Can a mindfulness-based stress-reduction course improve symptoms and wellbeing in young people aged 15-24 years with inflammatory bowel disease?

An evaluation of mindfulness-based stress reduction groups for adolescents and young adults with Crohn’s disease and ulcerative colitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN67022693

Enrollment

Registered

2019-09-12

Start date

2017-03-21

Completion date

Unknown

Last updated

2020-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory bowel disease Digestive System

Interventions

Participants will be randomly assigned to one of two groups. Group 1 will start the MBSR course immediately after recruitment and Group 2 will participate in the programme about 8 to 10 weeks later. T

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 15-24 years 2. Diagnosed with Crohn’s disease (CD) or ulcerative colitis (UC)

Exclusion criteria

Exclusion criteria: 1. Severe IBD 2. Currently experiencing severe psychological difficulties (e.g. psychosis, substance abuse or suicidality)

Design outcomes

Primary

Measure	Time frame
For CD patients: 1. Patient-reported symptoms assessed using the Harvey-Bradshaw Index (HBI) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) For UC patients: 2. Patient-reported symptoms assessed using the Paediatric Ulcerative Colitis Activity Index (PUCAI) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) 3. Patient-reported symptoms assessed using the Simple Clinical Colitis Activity Index (SCCAI) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) For all patients: 4. Haematological parameters, including full blood count and erythrocyte sedimentation rate, assessed before and after the intervention 5. C-reactive protein (CRP, a marker of inflammation) level in blood assessed before and after the intervention 6. Intestinal inflammation assessed using faecal calprotectin level before and after the intervention	—

Measure

Time frame

For CD patients: 1. Patient-reported symptoms assessed using the Harvey-Bradshaw Index (HBI) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) For UC patients: 2. Patient-reported symptoms assessed using the Paediatric Ulcerative Colitis Activity Index (PUCAI) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) 3. Patient-reported symptoms assessed using the Simple Clinical Colitis Activity Index (SCCAI) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) For all patients: 4. Haematological parameters, including full blood count and erythrocyte sedimentation rate, assessed before and after the intervention 5. C-reactive protein (CRP, a marker of inflammation) level in blood assessed before and after the intervention 6. Intestinal inflammation assessed using faecal calprotectin level before and after the intervention

—

Secondary

Measure	Time frame
1. Health-related quality of life specific to IBD assessed using the IMPACT-III Quality of Life Questionnaire at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) 2. Mindfulness assessed using the Mindful Attention Awareness Scale at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) 3. Mental wellbeing assessed using the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) 4. Perception of stress assessed using the Perceived Stress Scale (PSS) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1)	—

Measure

Time frame

1. Health-related quality of life specific to IBD assessed using the IMPACT-III Quality of Life Questionnaire at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) 2. Mindfulness assessed using the Mindful Attention Awareness Scale at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) 3. Mental wellbeing assessed using the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1) 4. Perception of stress assessed using the Perceived Stress Scale (PSS) at T0 (at recruitment), T1 (10 -12 weeks after recruitment) and T2 (10-12 weeks after T1)

—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026