Perioperative renal protection in patients subject to cardio-pulmonary bypass

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN66959365

Enrollment

Registered

2005-09-30

Start date

2003-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiopulmonary bypass Surgery Cardiopulmonary bypass

Interventions

To examine potential methods of protecting the kidney during and immediately after heart surgery using cardiopulmonary bypass.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged greater than 70 years 2. Pre-existing renal disease 3. Not on renal replacement therapy 4. Pre-operative serum creatinine greater than 130 umol/l 5. Type one diabetes mellitus

Exclusion criteria

Exclusion criteria: Only first time coronary artery surgery will be included

Design outcomes

Primary

Measure	Time frame
Determine whether perioperative low dose frusemide, dopamine or aminophylline would improve clinical and biochemical outcomes in adult patients, at increased risk of kidney dysfunction.	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026