Investigating the relationship between aortic aneurysms and air pollution using excess aortic samples from surgery and organ donors

InvestigAtion into the relAtionship between AortiC aneurysmaL disease and air pOllUtion using Intraoperative samples from live donors and cadaveric organ Donors (AAA-CLOUD)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN66813768

Enrollment

100

Registered

2023-03-31

Start date

2023-07-01

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal aortic aneurysm Circulatory System

Interventions

Many of the organs that become available for transplant are from patients relatively free of pre-existing vascular disease, the cause of death in such cases is usually traumatic or neurological and of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Undergoing open aneurysm repair or cadaveric kidney donor (death due to non vascular causes)

Exclusion criteria

Exclusion criteria: 1. No valid consent 2. Patients undergoing emergency surgery or in extremis

Design outcomes

Primary

Measure	Time frame
Level of magnetite in micrograms per gram of dry tissue measured using magnetic analyses at the time of sampling compared between aneurysm tissue and controls	—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026