Bronchiolitis Respiratory Bronchiolitis
Conditions
Interventions
Patients who entered the study were randomized to receive either nebulized epinephrine in hypertonic saline or nebulized epinephrine in normal saline. Each patient had his or her oxygen saturation lev
Sponsors
University of Alberta, Department of Pediatrics (Canada)
Eligibility
Inclusion criteria
Inclusion criteria: Infants 6 weeks to 12 months of age with clinical symptoms of a viral respiratory infection (coryza or temperature = 38.0°C), first episode of wheezing, oxygen saturation = 85% but = 96%, and initial Respiratory Distress Assessment Instrument (RDAI) score = 4.
Exclusion criteria
Exclusion criteria: Pre-existing cardiac or pulmonary disease, previous diagnosis of asthma by a physician, any previous use of bronchodilators, severe disease requiring resuscitation room care, inability to administer medication by nebulizer, inability to obtain informed consent secondary to a language barrier, or no phone access for follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Respiratory Assessment Change Score (RACS) was the primary outcome variable of the study. This score is a clinical scoring system based on the Respiratory Distress Assessment Index (RDAI) and the respiratory rate. | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygen saturation and rate of admission to hospital. | — |
Countries
Canada
Outcome results
None listed