Management of depression by primary care health workers in Lagos, Nigeria

Collaborative stepped care intervention with mobile telephone support for primary care workers’ management of depression in Lagos, Nigeria: A cluster randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN66243738

Enrollment

1350

Registered

2017-01-31

Start date

2014-07-01

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression Mental and Behavioural Disorders Depression

Interventions

Participating centers are randomized to one of the three groups by an independent centre using minimization procedure to ensure even distribution of the PHCs as per their size. Contro

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults aged 18-60 years 2. Scoring >10 on PHQ-9 or persistent score of >5 but <10 on PHQ-9 for 2 weeks 3. Intend to stay in the project area for at least 16 months 4. Ready to consent to trial

Exclusion criteria

Exclusion criteria: 1. Children (below 18 years) and the elderly (above 60 years) 2. Patients with serious medical condition or disability necessitating specialist care 3. Patients having presently having any form of psychosis or under psychiatric care or showing suicidal ideation or attempt. 4. Patients with scores 5 or less on PHQ-9 on first visit or 2 weeks repeat screen 5. Patients not intending to stay in the project area for at least 16 months

Design outcomes

Primary

Measure	Time frame
Depressive symptoms are measured using the Patient Health Questionnaire (PHQ-9) at 4, 6 and 12 months.	—

Secondary

Measure	Time frame
1. Disability due to the illness is measured using the Short form of the WHO Disability Assessment Schedule (WHODAS-S) at baseline, 6 and 12 months 2. Quality of life is measured using the Brief version of the WHO Quality of Life schedule (WHOQOL-Bref) at baseline, 6 and 12 months 3. Adherence to treatment instructions (clinic appointments and drug dosage) is measured using logs of attendance and tablet counts at 6 and 12 months 4. Death from suicide and rate of self-inflicted injuries at 6 and 12 months 5. Health economic cost is calculated using the Client Service Receipt Inventory at 6 and 12 months 6. Stigma experience by the patient will be measured using the 7-item Impact Scale of the Inventory of Stigma Experiences at baseline, 6 and 12 months	—

Measure

Time frame

1. Disability due to the illness is measured using the Short form of the WHO Disability Assessment Schedule (WHODAS-S) at baseline, 6 and 12 months 2. Quality of life is measured using the Brief version of the WHO Quality of Life schedule (WHOQOL-Bref) at baseline, 6 and 12 months 3. Adherence to treatment instructions (clinic appointments and drug dosage) is measured using logs of attendance and tablet counts at 6 and 12 months 4. Death from suicide and rate of self-inflicted injuries at 6 and 12 months 5. Health economic cost is calculated using the Client Service Receipt Inventory at 6 and 12 months 6. Stigma experience by the patient will be measured using the 7-item Impact Scale of the Inventory of Stigma Experiences at baseline, 6 and 12 months

—

Countries

Nigeria

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 2, 2026