Randomised controlled trial of patient controlled sedation for colonoscopy: entonox vs target controlled infusion of propofol

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN65879800

Enrollment

Registered

2007-09-28

Start date

2005-10-18

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery: Analgesia Surgery Analgesia

Interventions

Prospective RCT involving all patients undergoing elective colonoscopy at the Endoscopy Suite, Castle Hill Hospital.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients of both sexes undergoing elective colonoscopy will be recruited.

Exclusion criteria

Exclusion criteria: Patients with chronic pulmonary disease, history of colonic resection, intolerance to any of the drugs, unwilling to enter trial, ASA class IV, allergy to soybeans, eggs, history of seizure disorder, sleep apnoea, or difficult intubation, a short thin neck or the inability to open mouth widely.

Design outcomes

Primary

Measure	Time frame
Pain score on the visual analogue scale	—

Secondary

Measure	Time frame
Patient comfort, completion rate, time taken and complications, time to discharge and time for return of psychomotor function.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026