Depression Mental and Behavioural Disorders Depressive episode
Conditions
Interventions
General Practitioners Care:
The treatment protocol is set up according to The Dutch College of General Practitioners Practice Guideline (NHG- standard) and composed after reviewing the
GP?s can adapt the scheme to their own style or to special circumstances. The treatment consists of supportive contacts which can be combined with an antidepressant agent. The duration of the treatmen
Sponsors
Netherlands Organisation for Health Research and Development (ZonMw) (Netherlands)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients aged between 18 and 70 years and suffering from major depressive disorder (MDD) determined by an independent researcher with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I)
Exclusion criteria
Exclusion criteria: 1. Suffering (now and in the past as assessed by the SCID-I) from schizophrenia or bipolar disorder 2. Contra-indication for MDD treatment like mental retardation or terminal illness 3. Having trouble with the Dutch or English language 4. Severe suicidal thoughts 5. Receiving an active MDD treatment. Active treatment is defined as: 5.1. Antidepressive medication (except those who receive this in low dosage for pain complaints: Amitriptyline less than 50 mg, Nortriptyline less than 50 mg, bupropion[Zyban®]) 5.2. Psychotherapy 5.3. Supportive visits with the GP or social worker, except for diagnostic visits (less than 2)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Hamilton depression rating scale-17 by telephone 2. Patient Heath Questionnaire-9: patient rated. Score: 0 (ie, not at all) and 1 (ie, few days) 2 (ie, more than half the days) and 3 (ie, nearly every day) All primary outcomes are assessed at baseline, 6, 12 and 52 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Medical Outcomes Study 36- Item Short Form Health Survey, assessed at baseline, 12 and 52 weeks. | — |
Countries
Netherlands
Outcome results
None listed