A clinical trial to study the effects of Ayurvedic formulation Suved and Reimmugen (whole cow colostrum) in patients with atherosclerosis

A study to evaluate the results of integrative treatment (Ayurvedic capsules Suved and Reimmugen) for vascular disease

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN65795273

Enrollment

200

Registered

2016-11-07

Start date

2016-10-09

Completion date

Unknown

Last updated

2020-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vascular disease, atherosclerosis Circulatory System

Interventions

Patients are randomised to one of two groups: 1. Suved (Ayurvedic formulation, FDA India approved) and whole cow colostrum Reimmugen. Dosage decided by regular Ayurvedic use Suved 500m

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Males or females aged 18 or over with a diagnosis of vascular disease leading to IHD, CAD, CVD, DVT or PAD at any stage

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating women 2. Patients below age of 18 3. Acute IPD operative condition 4. Patients undergoing interventional procedures/surgical treatments other than for vascular disease, until they are discharged from intensive care 5. Haemorrhagic cerebrovascular stroke

Design outcomes

Primary

Measure	Time frame
Restoration of carotid IMT to a non-pathological state, supported with positive changes in functionality and relief from associated symptoms: 1. Clinical investigations will be compared pre - post treatment to evaluate percent changes in IMT and cardiac function as a mark of reversal of atherosclerosis and relief from symptoms associated with blockages in blood vessels due to atherosclerosis. IMT measurements are taken as standard to evaluate atherosclerosis and 2D echo taken for cardiac perfusion. 2. Functional changes considered on the basis of symptoms of chest pain, breathlessness, stamina of walking or performing daily chores. Measured at baseline and at the end of 3 months of treatment.	—

Measure

Time frame

Restoration of carotid IMT to a non-pathological state, supported with positive changes in functionality and relief from associated symptoms: 1. Clinical investigations will be compared pre - post treatment to evaluate percent changes in IMT and cardiac function as a mark of reversal of atherosclerosis and relief from symptoms associated with blockages in blood vessels due to atherosclerosis. IMT measurements are taken as standard to evaluate atherosclerosis and 2D echo taken for cardiac perfusion. 2. Functional changes considered on the basis of symptoms of chest pain, breathlessness, stamina of walking or performing daily chores. Measured at baseline and at the end of 3 months of treatment.

—

Secondary

Measure	Time frame
Development of ischaemic events in other circulations (e.g., in a stroke patient, evaluation of coronaries), assessed at baseline and at the end of 3 months of treatment.	—

Countries

India

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026