The N-methyl-D-aspartate (NMDA)-antagonist memantine affects training induced motor cortex plasticity: a study using transcranial magnetic stimulation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN65784760

Enrollment

Registered

2005-05-09

Start date

1998-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Training induced motor cortex plasticity Not Applicable

Interventions

Memantine versus placebo either given as a single dose or daily over 8 days.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy subjects (adults, either sex)

Exclusion criteria

Exclusion criteria: 1. Left-handedness 2. Neurological disorders 3. Intake of central acting drugs

Design outcomes

Primary

Measure	Time frame
The differential effects of different treatment regimens.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026