Acute stress in healthy young males Not Applicable
Conditions
Interventions
Randomized, blinded oral administration of 40 mg Atomoxetine + Hydrocortisone-Placebo, Atomoxetine-Placebo + 10 mg Hydrocortisone, 40 mg Atomoxetine + 10 mg Hydrocortisone, or Atomoxetine-Placebo + Hy
Sponsors
TU Dresden
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Male sex 2. Right-handed 3. Age 18-30 years 4. Normal or corrected-to-normal vision
Exclusion criteria
Exclusion criteria: 1. History of psychiatric disorders 2. Chronic medication use 3. Current nicotine dependence 4. Current drug consumption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Performance (response time and accuracy) is measured using a rapid-serial-visual-presentation task, a stop-signal task, a switch task, and a dual task over 90 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Cortisol exposure measured using Salivary Cortisone Levels over 90 minutes 2. (Nor-)epinephrine exposure measured using Blood Pressure and Heart Rate over 90 minutes 3. Mood, Awakeness, and Calmness measured using the Multidimensional Mood State Questionnaire (MDBF) over 90 minutes | — |
Countries
Germany
Outcome results
None listed