Chronic respiratory disease Respiratory
Conditions
Interventions
This is a 3-arm individually randomised implementation trial. Randomisation will be carried out by research staff using a web-based randomisation service managed by the Edinburgh Clinical Trials Unit
Sponsors
Accord (United Kingdom)
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Adults 18 years old (the age of majority in all the countries). No upper age limit. 2. Assessed by referring physician as having persistent and functionally limiting respiratory symptoms (mMRC 2) after optimisation of pharmacological therapy 3. Resident locally and willing to engage with either Centre-PR or Home-PR schedules if randomised to these groups 4. Willing and able to provide written informed consent
Exclusion criteria
Exclusion criteria: 1. People with non-respiratory causes for the symptoms (stable co-morbidity may be included if clinically appropriate) 2. Active TB infection 3. Any condition that would increase risk (e.g. uncontrolled cardiac disease) interfere with PR (e.g. neurological disorders, severe arthritis, dementia), or be inappropriate (very severe frailty, end-of-life) 4. On-going, or completed PR (including other exercise programme) within the previous 18 months 5. Living in the same house as another participant 6. Unwilling or unable to provide informed consent
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life measured using the St Georges Respiratory Questionnaire (SGRQ) at baseline, post-PR and 6 months | — |
Primary
| Measure | Time frame |
|---|---|
| Functional exercise capacity is measured by the Endurance Shuttle Walking Test (ESWT) at baseline, post- PR and 6 months. | — |
Countries
Bangladesh, India, Malaysia
Contacts
Public ContactVictoria Hammersley
Outcome results
None listed