Effects of aquatic training on knee cartilage

Conditions

Osteoarthritis Musculoskeletal Diseases Other arthrosis

Benjamin Waller, Matti Munukka, Timo Rantalainen, Eveliina Lammentausta, Miika T. Nieminen et al. (10 authors)

Osteoarthritis and Cartilage2017-03-0298 citations

10.1016/j.joca.2017.02.800

Efficacy of progressive aquatic resistance training for tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis: a randomised controlled trial.

Munukka M, Waller B, Rantalainen T, Häkkinen A, Nieminen MT, Lammentausta E, Kujala UM, Paloneva J, Sipilä S, Peuna A, Kautiainen H, Selänne H, Kiviranta I, Heinonen A.

2016-05-1955 citations

10.1016/j.joca.2016.05.007

Effects of a progressive aquatic resistance exercise program on the biochemical composition and morphology of cartilage in women with mild knee osteoarthritis: protocol for a randomised controlled trial.

Waller B, Munukka M, Multanen J, Rantalainen T, Pöyhönen T, Nieminen MT, Kiviranta I, Kautiainen H, Selänne H, Dekker J, Sipilä S, Kujala UM, Häkkinen A, Heinonen A.

2013-03-0719 citations

10.1186/1471-2474-14-82

Interventions

The study will be a 4-month, randomized controlled study (RCT) in postmenopausal women with mild OA who will be randomly assigned into two groups: 1. An aquatic exercise group

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Voluntary women 60-68 years of age, regular intensive exercise (such as strength training) no more than two times a week 2. No history of any illness for which exercise is contraindicated or that would limit their participation in the Aquatic exercise program 3. Subjects with mild to moderate knee pain during the last 12 months 4. Willingness and voluntarily signed informed consent to undergo testing and intervention procedures with all of its aspects 5. Weight-bearing knee x-rays show Kellgren-Lawrence grade 1-2 OA according to Altman et al.(1986)

Exclusion criteria

Exclusion criteria: 1. Body-mass index over 34 2. Knee instability or trauma that would jeopardize the training 3. Inflammatory joint disease 4. Intra-articular steroid injections in the preceding 3 months in the knee

Design outcomes

Primary

Measure	Time frame
Cartilage measurements Structural changes of the tibiofemoral and patella cartilage will be revealed by Magnetic Resonance Imaging (MRI) at 1.5T magnetic field strength. The combination of two techniques will be used, T2 relaxation time, indexing the collagen component of cartilage, and dGEMRIC, reflective of glycosaminoglycan concentration, volumetric MRI assessment of cartilage thickness and morphology. Also, the quality of subchondral bone will be evaluated. In our laboratory, the reproducibility of bulk dGEMRIC is good (CVrms 4.2 ?4.8%) Body composition: Dual energy X-ray absorptiometry (DXA) will be performed to assess body composition. The body fat, lean body mass as well as femoral neck and lumbar spine areal bone mineral density (BMD, g/cm2) and bone mineral content (BMC, g) will be analyzed.	—

Measure

Time frame

Cartilage measurements Structural changes of the tibiofemoral and patella cartilage will be revealed by Magnetic Resonance Imaging (MRI) at 1.5T magnetic field strength. The combination of two techniques will be used, T2 relaxation time, indexing the collagen component of cartilage, and dGEMRIC, reflective of glycosaminoglycan concentration, volumetric MRI assessment of cartilage thickness and morphology. Also, the quality of subchondral bone will be evaluated. In our laboratory, the reproducibility of bulk dGEMRIC is good (CVrms 4.2 ?4.8%) Body composition: Dual energy X-ray absorptiometry (DXA) will be performed to assess body composition. The body fat, lean body mass as well as femoral neck and lumbar spine areal bone mineral density (BMD, g/cm2) and bone mineral content (BMC, g) will be analyzed.

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Secondary

Measure	Time frame
1. Knee pain will be evaluated by a 100 mm visual analog scale (VAS) 2. Physical function and clinically-important symptoms will be evaluated by Knee Injury and Osteoarthritis 3. Knee Injury and Osteoarthritis Outcome Score (KOOS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) 4. X-ray (weight-bearing anteroposterior and mediolateral radiographs) will be taken from both knees for the classification of osteoarthritis of the knee 5. Quality of life will be evaluated by the RAND 36-Item Health Survey questionnaire 6. Muscle strength (leg extension and flexion) will be measured using an adjustable dynamometer chair (Good Strength; Metitur, Jyväskylä, Finland) 7. Muscle power will be measured with a Nottingham powerrig 8. Dynamic balance and agility will be evaluated with a timed figure of 8 running test	—

Measure

Time frame

1. Knee pain will be evaluated by a 100 mm visual analog scale (VAS) 2. Physical function and clinically-important symptoms will be evaluated by Knee Injury and Osteoarthritis 3. Knee Injury and Osteoarthritis Outcome Score (KOOS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) 4. X-ray (weight-bearing anteroposterior and mediolateral radiographs) will be taken from both knees for the classification of osteoarthritis of the knee 5. Quality of life will be evaluated by the RAND 36-Item Health Survey questionnaire 6. Muscle strength (leg extension and flexion) will be measured using an adjustable dynamometer chair (Good Strength; Metitur, Jyväskylä, Finland) 7. Muscle power will be measured with a Nottingham powerrig 8. Dynamic balance and agility will be evaluated with a timed figure of 8 running test

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Countries

Finland

Outcome results

None listed