Cracked nipples colonized with Staphylococcus aureus: a randomised treatment trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN65289389

Enrollment

Registered

2002-12-09

Start date

2001-11-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mastitis (prevention of) in lactating women Pregnancy and Childbirth Mastitis

Interventions

Women with nipple swab positive for Staphylococcus aureus are randomised to receive a seven-day course of: 1. Flucloxacillin 500 mg qid, or 2. Identical placebo capsules

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Breastfeeding women with at least one damaged nipple 2. English-speaking 3. Live in Melbourne 4. Not allergic to penicillin

Exclusion criteria

Exclusion criteria: Not provided at time of registration.

Design outcomes

Primary

Measure	Time frame
Incidence of mastitis in each group in the week following recruitment.	—

Secondary

Measure	Time frame
Nipple healing, nipple pain.	—

Countries

Australia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 5, 2026