Critical illness
Conditions
Interventions
A proprietary 5% tea tree oil-enriched body wash preparation versus standard body wash (Johnson's pH 5.5). The duration of treatment is for the length of the patient's ICU stay. Follow up will be unti
Sponsors
Belfast Health and Social Care Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients admitted to the Intensive Care Unit (ICU) during the study period will be eligible for inclusion in the study.
Exclusion criteria
Exclusion criteria: 1. Aged less than 16 years 2. Those patients who are known to be colonised at the time of admission 3. Patients who on admission are unlikely to remain in the Respiratory Intensive Care Unit (RICU) for at least 48 hours 4. Patients who are recruited, whose pre-intervention MRSA screening tests are subsequently found to be positive, will be withdrawn from the study 5. Consent declined 6. Known sensitivity to TTO
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| New MRSA colonisation during the inpatient episode in RICU, as defined by detection of MRSA by conventional culture methods in screening swabs of nose and groin, or in clinical specimens processed by the laboratory in the course of normal clinical care. This will be measured on discharge from the ICU. | — |
Secondary
| Measure | Time frame |
|---|---|
| All measured on discharge from the ICU: 1. Cost-effectiveness of regular use of 5% TTO body wash in this context 2. MRSA bacteraemia rates 3. Consumption of antibiotics used for the treatment of MRSA infection 4. Changes in the Sequential Organ Failure Assessment (SOFA) score during ICU stay | — |
Countries
United Kingdom
Outcome results
None listed