Pneumothorax in newborn infants Neonatal Diseases Pneumothorax originating in the perinatal period
Conditions
Interventions
Aspiration with a 23 or 25 gauge "butterfly" needle and 20mL syringe versus chest drain insertion.
Acute intervention (up to 15 minutes). Follow-up until hospital discharge.
Sponsors
The National Maternity Hospital (Ireland)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Infants (term and preterm) will be eligible for enrolment in the study if they 1. Have a pneumothorax diagnosed on chest x-ray by treating clinicians 2. Are receiving respiratory support 2.1. Mechanical ventilation (conventional or high frequency oscillation) 2.2. Continuous positive airway pressure (CPAP) 2.3. Supplemental oxygen FiO2 > 40% by head box or nasal cannulae to keep SpO2 >90% 3. The treating clinicians deem the pneumothorax requires treatment
Exclusion criteria
Exclusion criteria: Infants will be excluded from the study if they: 1. Do not have respiratory distress 2. Have significant pulmonary hypoplasia, e.g. Potter's sequence
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chest drain insertion for management of pneumothorax on chest x-ray within 6 hours of diagnosis. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Duration of chest drain 2. Number of chest drain insertions 3. Duration of ventilation post intervention 4. Duration of ventilation 5. Duration of nasal continuous positive airway pressure 6. Duration of supplemental oxygen 7. Bronchopulmonary dysplasia ? oxygen treatment at 28 days 8. Chronic lung disease ? oxygen treatment at 36 weeks post menstrual age 9. Nosocomial infections 10. Pleural effusions 11. Duration of hospital stay 12. Death before discharge from hospital | — |
Countries
Australia, Germany, Ireland, Italy, Netherlands, Norway, Sweden
Outcome results
None listed