Surgical excision versus Mohs micrographic surgery for primary and recurrent basal cell carcinoma of the face

Examining the (cost-) effectiveness of Mohs micrographic surgery versus surgical excision in the treatment of primary and recurrent basal cell carcinoma: a prospective randomised study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN65009900

Enrollment

612

Registered

2008-10-27

Start date

1999-11-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary or first or second recurrent basal cell carcinoma Cancer Basal cell carcinoma

Interventions

Arm 1: Mohs micrographic surgery - Tumours were excised with a margin of 3 mm under an angle of 45 degrees. The complete resection margins of the excised material were investigated histopathologically

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Primary or first or second recurrent basal cell carcinoma 2. Aged 18 years or older, either sex

Exclusion criteria

Exclusion criteria: Expected life-duration of less than 3 years

Design outcomes

Primary

Measure	Time frame
Recurrence of carcinoma after 5 years follow-up	—

Secondary

Measure	Time frame
1. Determinants of failure after 5 years of follow-up, tested with Cox regression analysis 2. Cost-effectiveness after 5 years of follow-up an incremental cost-effectiveness ratio was calculated, all personal and material costs of both treatments that have been made during procedures and follow-up were calculated by multiplying volumes of use with the cost per unit	—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 4, 2026