Acute Heart Failure (AHF) Registry Würzburg

Prospective cohort study on etiology, clinical Features, costs, palliative needs and outcomes in acute heart failure

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN65006275

Enrollment

1000

Registered

2014-10-16

Start date

2014-08-01

Completion date

Unknown

Last updated

2021-09-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute heart failure Circulatory System

Interventions

There is no intervention in this study. The data collection for the AHF Registry Würzburg does not interfere with any routine diagnostic or therapeutic procedures. There are no additional study-relate

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age >18 years 2. Hospitalization with AHF (de novo/decompensated chronic HF) according to the clinical judgment of the responsible physician 3. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Cardiogenic shock 2. High output heart failure 3. On waiting list for urgent HTX

Design outcomes

Primary

Measure	Time frame
Incidence of post-discharge events (re-hospitalization and cause-specific death) during the observation period	—

Secondary

Measure	Time frame
1. Proportion of patients with HFrEF versus HFpEF at the time of the index hospitalization 2. Proportion of patients with HFrEF versus HFpEF versus other aetiologies including reversible HF (e.g. arrhythmogenic) at the time of discharge from hospital after the index hospitalization 3. Proportion of patients with de novo versus decompensated chronic HF at the index hospitalization 4. Frequency of diagnosis of different HF etiologies at the time of index hospitalization 5. Time course of re-hospitalization events (all-cause and HF-related, duration of hospital stays and time intervals between consecutive re-hospitalization events) and incidence of cause-specific death after the index hospitalization 6. Time alive and out of hospital 7. Prevalence of advanced HF at index hospitalization 8. Incidence of advanced HF during follow-up 9. Clinical course and outcomes of patients with advanced HF according to different treatment patterns (e.g. surgical versus medical only) 10. Incidence of the transition from HFrEF to HFpEF and vice versa during long-term follow-up 11. Prevalence, severity and correlates of anxiety, depression, cognitive impairment, and impairment of quality of life during the index hospitalization and during long-term follow-up 12. Differential impact of co-morbidities on short-term and long-term outcomes	—

Measure

Time frame

1. Proportion of patients with HFrEF versus HFpEF at the time of the index hospitalization 2. Proportion of patients with HFrEF versus HFpEF versus other aetiologies including reversible HF (e.g. arrhythmogenic) at the time of discharge from hospital after the index hospitalization 3. Proportion of patients with de novo versus decompensated chronic HF at the index hospitalization 4. Frequency of diagnosis of different HF etiologies at the time of index hospitalization 5. Time course of re-hospitalization events (all-cause and HF-related, duration of hospital stays and time intervals between consecutive re-hospitalization events) and incidence of cause-specific death after the index hospitalization 6. Time alive and out of hospital 7. Prevalence of advanced HF at index hospitalization 8. Incidence of advanced HF during follow-up 9. Clinical course and outcomes of patients with advanced HF according to different treatment patterns (e.g. surgical versus medical only) 10. Incidence of the transition from HFrEF to HFpEF and vice versa during long-term follow-up 11. Prevalence, severity and correlates of anxiety, depression, cognitive impairment, and impairment of quality of life during the index hospitalization and during long-term follow-up 12. Differential impact of co-morbidities on short-term and long-term outcomes

—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026