Topic: Respiratory
Conditions
Interventions
1. Pulmonary Rehabilitation: Six week programme, twice weekly
2. Tiotropium, Exercise test sensitivity to the addition of Tiotropium
3. Control: No intervention
Sponsors
Glenfield Hospital (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 25/01/2016: 1. Confirmed diagnosis of COPD (COPD Gold Stage II ? Gold IV) 2. MRC grade dyspnoea >2 3. Aged 40 - 85 years, male & female Previous inclusion criteria: 1. Confirmed diagnosis of COPD (COPD Gold Stage II ? Gold IV) 2. MRC grade dyspnoea >3 3. Aged 40 - 85 years, male & female
Exclusion criteria
Exclusion criteria: 1. Co-morbidity that limits the ability to walk/cycle (e.g. musculoskeletal, arthritic, or neurological disorders) 2. Participation in rehabilitation over the last 12 months 3. Patients on long term oxygen therapy 4. Patients requiring oxygen therapy during the course of an exercise test (i.e. de-saturation documented below 85%)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vo2 Peak measured at baseline and post Intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Work Load, Duration, Heart Rate, SpO2, Distance, Borg Breathlessness Scale, Strength (kg), Gait Speed, function scores & Health related Quality of Life. | — |
Countries
United Kingdom
Outcome results
None listed