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Allogeneic demineralized dentin matrix to preserve the alveolar dimensions after teeth extraction

Allogeneic demineralized dentin matrix prepared from human-extracted teeth as a bone graft to preserve the alveolar dimensions after teeth extraction: A randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN64692193
Enrollment
8
Registered
2025-03-28
Start date
2023-10-02
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preservation of the alveolar ridge dimensions Oral Health

Interventions

The study sample consisted of thirty-four bilateral mandibular alveolar sockets for eight patients whose teeth were indicated for extraction. The sample was randomly divided into two groups: • Group 1

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthy participants. 2. Participants aged 18-40 years. 3. Participants required bilateral simple extraction of mandibular teeth.

Exclusion criteria

Exclusion criteria: 1. Participants with cystic and/or large periapical lesions at the site of extraction. 2. Participants with periodontal diseases and/or poor oral hygiene. 3. Pregnant or breastfeeding women. 4. Heavy smokers, alcoholic participants, and/or tobacco chewers. 5. Patients recently underwent radiation or chemical therapy.

Design outcomes

Primary

MeasureTime frame
The dimensional radiographic changes in width and height of the alveolar ridge were evaluated utilizing a cone beam computed tomography (CBCT) scan. The first CBCT scan was obtained immediately postoperatively (t1), and the second CBCT scan six months later (t2).

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

Syria

Contacts

Public ContactMawia Karkoutly
mawia95.karkoutly@damascusuniversity.edu.sy+963 992647528

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026