Assessment of neuroendocrine responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa

Assessment of neuroendocrine responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa: an observational case-control study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN64683774

Enrollment

Registered

2014-09-29

Start date

2011-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia nervosa Mental and Behavioural Disorders Anorexia nervosa

Interventions

Before the first experimental session, each participant was asked to indicate his more favorite food by answering the following question: ?Which is your most favorite food that you would eat also when

then they received a breakfast of 300 kcal. Immediately after breakfast, participants rated again their hunger and satiety by means of VAS. After 1 h, they were told that they would receive their prev

at the end of the exposure, participants were asked to rate their hunger, satiety, urge to eat that food, pleasantness to experience a mouthful of that food and amount of food they would eat by means

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Diagnosis of current or past anorexia nervosa (using the Structured Clinical Interview for DSM-IV Axis I disorders-patient edition) 2. Male and female patients aged 18?40 years 3. BMI =18.5 kg/m² in patients with current anorexia nervosa 4. BMI = 18.5 kg/m² in patients with weight-restored anorexia nervosa 5. Male and female normal weight healthy subject aged 18-40 years

Exclusion criteria

Exclusion criteria: 1. Participants who do not satisfy inclusion criteria 2. Participants currently treated with hormones or drugs, with a history of psychosis, diabetes mellitus, active substance use or head trauma, presence of severe physical disorders or comorbid psychiatric disorders

Design outcomes

Primary

Measure	Time frame
Response patterns of endocannabinoids and endocannabinoid-related substances to hedonic and non-hedonic eating in patients with acute and weight-restored AN and in healthy subjects. Analyzed at time the blood sample is taken.	—

Secondary

Measure	Time frame
Response patterns of other food-related reward biochemical mediators (ghrelin, cortisol) to hedonic and non-hedonic eating. Analyzed at time the blood sample is taken.	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 18, 2026